combo-product-test

Identify the number of complete, partial or minimal HLA matching umbilical cord blood units available for a stem cell transplant

• What's Tested?
  A stem cell transplant utilising umbilical cord blood requires checking for immunological compatibility between donor and patient (medically known as HLA or Human Leukocyte Antigen matching) at 4 different genetic locations.

  Sample Analysed

  Recipient: Saliva sample (for adults) or alternatively dried blood spot from a finger prick are required for testing

  Donor: A few drops of the preserved umbilical cord blood unit are utilised for testing

  HLA Parameters Tested

  LifeCell utilises next generation sequencing to provide high resolution HLA typed results for a total of 8 parameters i.e. two genes with 4 locations for each gene namely HLA A, B, C, DR

  Learn More
• Is This Test Right For Me?
  Several reasons could be the trigger for initiating a search - either for a current or potential future medical need.

  Transplant Requirement

  When a loved one is unfortunately diagnosed of a condition treatable using stem cells, depending on patient’s disease progress and treatment response, they may require a stem cell transplant from a healthy matched donor

  Proactive Search

  Knowledge is power and knowing how many matches are available especially for those who have pre-exisiting family history. Having access to results also helps accelerate the time to a transplant if needed in the future.

  Learn More
• Results And Recommendations
  LifeCell maintains India's largest repository of ready to use stem cells and the matching results from the search are updated as upto the accession date.

  Matches Found

  The number of matching umbilical cord units within LifeCell’s Community inventory are reported based on various degrees of match found

  • Perfect Match (8/8 Match)
  • Partial Match (7/8 Match)
  • Acceptable Match (6/8 Match)

  Additional Information

  Transplant physician’s may also prioritise the quantity of stem cells and may also check for red cell compatibility. LifeCell provides this additional information including donor identification details along with your reported results to help your physician choose the best units.

  Annual Updates:

  LifeCell’s inventory continues to grow on a regular basis and hence we strive to provide you with updated position of matches on an annual basis at no additional charge as long as you’re still an active member of the LifeCell community registry

  Extended Search

  When Requested LifeCell can also support search for matching units or donors within third party registries available worldwide for a both adult marrow and umbilical cord blood units.

• Collection Process
  • 1

    Collect

  • 2

    Fill Form

  • 3

    Dispatch

• What's Tested?
  A stem cell transplant utilising umbilical cord blood requires checking for immunological compatibility between donor and patient (medically known as HLA or Human Leukocyte Antigen matching) at 4 different genetic locations.

  Sample Analysed

  Recipient: Saliva sample (for adults) or alternatively dried blood spot from a finger prick are required for testing

  Donor: A few drops of the preserved umbilical cord blood unit are utilised for testing

  HLA Parameters Tested

  LifeCell utilises next generation sequencing to provide high resolution HLA typed results for a total of 8 parameters i.e. two genes with 4 locations for each gene namely HLA A, B, C, DR

  Learn More
• Is This Right For Me?
  Several reasons could be the trigger for initiating a search - either for a current or potential future medical need.

  Transplant Requirement

  When a loved one is unfortunately diagnosed of a condition treatable using stem cells, depending on patient’s disease progress and treatment response, they may require a stem cell transplant from a healthy matched donor

  Proactive Search

  Knowledge is power and knowing how many matches are available especially for those who have pre-exisiting family history. Having access to results also helps accelerate the time to a transplant if needed in the future.

  Learn More
• Results and Recommendations
  LifeCell maintains India's largest repository of ready to use stem cells and the matching results from the search are updated as upto the accession date.

  Matches Found

  The number of matching umbilical cord units within LifeCell’s Community inventory are reported based on various degrees of match found

  • Perfect Match (8/8 Match)
  • Partial Match (7/8 Match)
  • Acceptable Match (6/8 Match)

  Additional Information

  Transplant physician’s may also prioritise the quantity of stem cells and may also check for red cell compatibility. LifeCell provides this additional information including donor identification details along with your reported results to help your physician choose the best units.

  Annual Updates:

  LifeCell’s inventory continues to grow on a regular basis and hence we strive to provide you with updated position of matches on an annual basis at no additional charge as long as you’re still an active member of the LifeCell community registry

  Extended Search

  When Requested LifeCell can also support search for matching units or donors within third party registries available worldwide for a both adult marrow and umbilical cord blood units.

• Collection Process Video
  • 1

    Collect

  • 2

    Fill Form

  • 3

    Dispatch

With Familyfloater; your siblings, their spouses, as well as their children can enjoy the life-saving benefits of community banking and get access to the largest registry of Indian origin stem cells without needing to have a baby themselves.

• What’s Included?
  All LifeCell community banking members who wish to share the protection of community stem cell banking to their extended family’s health can now do so at a very affordable price and without necessarily needing to have made a personal contribution themselves to the community.

  Finding a Matched Unit

  LifeCell’s inventory of > 60,000 qualified units available for matching within the community registry is the largest in the country, thereby providing highest chances (>97%) of finding a suitably matched unit

  Free search for matching stem cells within LifeCell Community Inventory (StemMatch) & also within other registries worldwide.

  Learn More

  Release for Transplant

  With Familyfloater, an unlimited number of matching units are also available for withdrawal by the parents’ siblings, (even siblings who have not yet planned a family) their spouse and grown up children (>2 years), 2 years post enrolment.

  Release is subject to usage in treatment of approved indications and registered clinical trials.

  Learn More

  Other Benefits

  Treatment for 82+ life-threatening disorders.

  Unlimited sample retrievals at no extra cost

  Free comprehensive pre-release testing & free worldwide shipment of matched units for transplant.

  Quality guarantee & disaster relief.

  Familyfloater Tree

  Biological Siblings

  Their Spouses

  Biological Children

• Why Choose Familyfloater?
  It is a once in a lifetime chance for your extended family members to benefit from the opportunity of having access to a pristine and precious source of stem cells which has several advantages compared to other sources.

  Significant Need for Stem Cells

  Below is the risk of an individual being diagnosed of common blood cancers at some point in a lifetime*:

  • Leukemia: 1 in 62
  • Non-Hodgkin Lymphoma: 1 in 48
  • Myeloma: 1 in 125

  India has a high burden of inherited red cell diseases such as Thalassemia & Sickle Cell Disease (2.5 Lakh patients) where stem cell transplant is the only curative treatment option

  *As per National Cancer Institute, Surveillance, Epidemiology and End Results Program

  Learn More

  Cord is Easier to Match

  For stem cell matching there are between 6-10 parameters that need to be matched, with each parameter having between 2000-4000 variants.

  Adult bone marrow requires 9-10 parameters to be matched.

  However Umbilical Cord Blood requires only 6-8 parameters to be matched thereby making it 10-100x more easier to find a match.

  Learn More

  Readily Available & No Additional Cost

  Umbilical Cord blood stem cells being frozen are 100% available and ready for immediate release. Further withdrawal of matching units from the community inventory is totally free.

  Even in advanced countries like the US about 50% of registered adult donors back out at the time of medical need. In some cases, since the donor is required to travel, there could be delays in access. Further there are significant costs in making arrangements for sourcing these cells.

  Recommended by Experts

  Community cord blood banking has the benefits of both private banking and public banking and hence is a superior option.

  Know More

  No wonder it’s supported by leading medical experts unlike private banking which has been criticised- as inherited disorders make it unfit for baby’s own use & can only be withdrawn once for family use.

  Public cord blood banks in India have limited inventory and are not growing due to lack of financial aid. Further they charge upto ₹10 lakhs for releasing a matching unit.

  Increasing Success Rates with Cord Blood

  Success rates for cord blood transplants are improving with each passing year due to innovations such as:

  • Improved chemotherapy regimens that have led to lower transplant related mortality, lesser rejections, earlier patient discharge and lower complications
  • Multiplying the number of cord blood stem cells in the lab or supplementing them with other stem cell sources has shown to accelerate the time to immune recovery without increase in side effects

  Learn More

  Limited Indian-Origin Donors & Units

  Representation of adult donors of Indian origin is less than 1% in global registries, and size of Indian donor registries is significantly sub-optimal (<1 Million Donors) to provide reasonable access to a matching donor

  Inventory of cord blood units within public banks in India is still very small (<10,000 units collectively)

• Treatable Conditions
  Over 50,000 stem cell transplants occur worldwide each year for treatment of 90+ conditions approved currently, and the researchers are continuing to investigate its use in several more indications.

  Inherited Blood Disorders

  Acute Myelofibrosis

  Agnogenic Myeloid Metaplasia

  Amyloidosis

  Aplastic Anemia

  Beta Thalassemia Major

  Blackfan-Diamond Anemia

  Congenital Amegakaryocytic Thrombocytopenia

  Congenital Cytopenia

  Congenital Dyserythropoietic Anemia

  Dyskeratosis Congenita

  Essential Thrombocythemia

  Fanconi Anemia

  Glanzmann’s Thrombasthenia

  Myelodysplastic Syndrome

  Paroxysmal Nocturnal Hemoglobinuria

  Polycythemia Vera

  Pure Red Cell Aplasia

  Refractory Anemia with Excess Blasts

  Refractory Anemia with Excess Blasts in Transition

  Refractory Anemia with Ringed Sideroblasts

  Shwachman-Diamond Syndrome

  Sickle Cell Disease

  Inherited Immune Disorders

  Adenosine Deaminase Deficiency

  Bare Lymphocyte Syndrome

  Chediak-Higashi Syndrome

  Chronic Granulomatous Disease

  Congenital Neutropenia

  DiGeorge Syndrome

  Evans Syndrome

  Fucosidosis

  Hemophagocytic Lymphohistiocytosis

  Hemophagocytosis Langerhans’ Cell Histiocytosis

  IKK Gamma Deficiency

  Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-linked Syndrome

  Kostmann Syndrome

  Myelokathexis

  Omenn Syndrome

  Phosphorylase Deficiency

  Purine Nucleoside

  Reticular Dysgenesis

  Severe Combined Immunodeficiency Diseases

  Thymic Dysplasia

  Wiskott-Aldrich Syndrome

  X-linked Agammaglobulinemia

  X-Linked Hyper IgM Syndrome

  X-Linked Lymphoproliferative Disorder

  Inherited Errors in Metabolism

  Congenital Erythropoietic Porphyria (Gunther Disease)

  Gaucher Disease

  Hunter Syndrome

  Hurler Syndrome

  Krabbe Disease

  Lesch-Nyhan Syndrome

  Mannosidosis

  Maroteaux-Lamy Syndrome

  Metachromatic Leukodystrophy

  Mucolipidosis II

  Neuronal Ceroid Lipofuscinosis

  Niemann-Pick Disease

  Sandhoff Disease

  Sanfilippo Syndrome

  Scheie Syndrome

  Sly Syndrome

  Tay Sachs

  Wolman Disease

  X-Linked Adrenoleukodystrophy

  Blood Cancers

  Acute Biphenotypic Leukemia

  Acute Lymphocytic Leukemia

  Acute Myelogenous Leukemia

  Acute Undifferentiated Leukemia

  Adult T Cell Leukemia/Lymphoma

  Chronic Active Epstein Barr

  Chronic Lymphocytic Leukemia

  Chronic Myelogenous Leukemia

  Chronic Myelomonocytic Leukemia

  Juvenile Chronic Myelogenous Leukemia

  Juvenile Myelomonocytic Leukemia

  Myeloid/Natural Killer Cell

  PrecursorAcute Leukemia

  Non-Hodgkin’s Lymphoma

  Prolymphocytic Leukemia

  Leukocyte Adhesion Deficiency

  Rhabdomyosarcoma

  Thymoma

  Wilms Tumor

  Conditions Under Clinical Trial

  Autism

  Cerebral Palsy

  Spinal Cord Injury

  Parkinson's Disease

  Lupus

  Crohn's Disease

  Rheumatoid Arthiritis

  Diabetes Type 1 & 2

  Lysosomal Storage Disease

  HIV

  Osteoarthritis

  Peripheral Arterial Disease

  Alzheimer's disease

  Encephalopathy

  Global Developmental Delay

  Hearing Loss (acquired sensorineural)

  Intraventricular Hemorrhage

  Stroke

  Traumatic Brain Injury

  Alopecia Areata

  Amyotrophic Lateral Sclerosis

  Eczema (Atopic Dermatitis)

  Graft-versus-Host Disease

  Systemic Sclerosis

  Critical Limb Ischemia

  Aging Frailty

  Epidermolysis Bullosa

  Severe Combined Immunodeficiency

  Tay-Sachs Disease

  Cartilage Injury

  Osteochondral Lesion

  BronchoPulmonary Dysplasia

  Eye Diseases

  Liver Failure

  Premature Ovarian Failure